First of its kind sleep measurement tool to help simplify diagnostic process for physicians
Innovative research from leading sleep scientists Dr. Magdy Younes and associates using novel EEG metric Odds Ratio Product (ORP) as a measure of sleep quality has revealed new insights into clinical symptoms of sleep disorders not detected through conventional metrics.
The research will be a gamechanger in helping physicians make more informed diagnosis in patients with sleep disorders, resulting in better treatment and patient outcomes. The paper, titled Sleep Architecture Based on Sleep Depth and Propensity: Patterns in Different Demographics and Sleep Disorders and Association with Health Outcomes in SLEEP identifies nine base ORP Sleep Architecture profiles which provide a framework to assist in diagnosing, managing, and understanding the underlying mechanisms of sleep disorders. ORP Sleep Architecture provides physicians with an easy to use visual point of reference while diagnosing patients and prescribing treatment based on the nine profile types with suggested interpretation and clinical implications. This is key to moving this advanced diagnostic technology into clinical practice.
Dr. Younes, Scientific Founder of Cerebra, comments on the research, “The evaluation of sleep quality and depth has been based on guidelines and technology developed in the 1960’s. This paper represents a new approach to look at sleep, employing new digital technology that presents sleep architecture as a way to identify potential underlying mechanisms of sleep disorders with the potential to advance their management.”
The additional information provided by ORP is sensitive enough to show variations in sleep quality traditional sleep stages are unable to detect. This unique aspect of ORP is further supported by a publication titled A novel EEG marker predicts perceived SLEEPINESS AND poor sleep quality, it observes how high ORP wake is predictive of perceived sleepiness and poor sleep quality in two large population cohorts and shows promise as a biomarker of hyperarousal and insomnia.
ORP micro analyzes the EEG signal, moving beyond conventional scoring methods to dig deeper into brain activity during sleep. ORP is a continuous metric of sleep depth ranging from 0 (very deep sleep) to 2.5 (full wakefulness). It has been validated as the most accurate measure of sleep depth and more strongly correlates to both clinical and self-reported symptoms of sleep disorders.
When presented as an architecture, ORP is broken down into 10 deciles ranging from 0-2.5. The deciles reflect the amount of time spent in different sleep depths across the night, creating a pattern of the patient’s sleep profile. The shape of the sleep profile describes a patient’s sleep quality; represented by the deep sleep deciles on the left, balanced by the wake deciles on the right.
ORP is licensed exclusively to Cerebra and is available through the Cerebra Sleep System, a fully self–applied, in-home PSG. The system is comparable to an in-lab study and is currently available for clinical use in Canada. USA FDA clearance is pending and anticipated to be granted in early mid-2022.
For more information, contact:
Karli Struss
Marketing and Communications Manager, Cerebra
1-204-805-3518
karli.struss@cerebrahealth.com
About Cerebra
Cerebra Medical Ltd. is a Canadian technology company transforming the future of sleep diagnosis and therapy. Cerebra unites innovators and researchers with the common goal and passion of putting “sleep” back into sleep medicine.
Cerebra Sleep System uses the patented algorithm, Odds Ratio Product (ORP) that micro analyses the Electroencephalogram (EEG) signal providing a continuous measure of sleep depth, moving beyond conventional scoring methods to dig deeper into brain activity. As a leader in sleep diagnostic technology, our innovative Cerebra Sleep System provides sleep researchers and clinicians with accurate, self-applied, in-home diagnostics.